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Postpartum Depression FAQs: How Moms Can Find Help and Treatment

By Pacific Neuroscience Institute® (PNI) in Santa Monica April 1, 2025

First of all, it’s important to remember that having postpartum depression (PPD) does not mean you are a failure as a mother. This is a common medical condition that affects many women, and it is not your fault. Seeking help is a sign of strength, and treatment can make a real difference. You are not alone, and support is available. Explore this article to learn more.

What is postpartum depression?

Postpartum depression is a serious mood disorder that can affect women after childbirth. Unlike the more common and temporary “baby blues,” which typically resolve within two weeks, PPD can last much longer and significantly impact a mother’s ability to care for herself and her baby.

What are the symptoms of postpartum depression?

Common symptoms include:

  • Persistent sadness or hopelessness
  • Severe mood swings
  • Excessive crying
  • Difficulty bonding with the baby
  • Changes in appetite or sleep patterns
  • Fatigue or loss of energy
  • Anxiety or panic attacks
  • Thoughts of self-harm or harming the baby

postpartum depression treatment

What causes postpartum depression?

The exact cause of PPD isn’t fully understood, but contributing factors include:

  • Hormonal changes after childbirth
  • Sleep deprivation
  • Emotional stress and anxiety
  • A personal or family history of depression or other mood disorders

How is postpartum depression different from baby blues?

  • Baby blues: Mild mood swings, irritability, and anxiety that typically resolve within two weeks postpartum. Common, affecting up to 80% of new mothers.
  • Postpartum depression: More severe and persistent symptoms that can last for months if untreated and interfere with daily life. Affects 1 in 7 women.

What are the treatment options for postpartum depression?

  • Therapy: Talk therapy or cognitive behavioral therapy (CBT) can be very effective.
  • Medication: Antidepressants may be prescribed and are often safe to use while breastfeeding.
  • Lifestyle changes: Regular exercise, healthy eating, and adequate rest.
  • Psychedelic-assisted therapy: Under expert supervision in a medical clinic.

Are there clinical trials for postpartum depression?

Yes. Innovative clinical trials are exploring new treatment options such as psychedelic-assisted therapy for postpartum depression and other mood disorders.

What should I know about psychedelic-assisted therapy?

The psychedelic experience is carefully guided and limited to the clinic visit, under the close supervision of trained medical professionals. This ensures safety, comfort, and therapeutic support throughout the process, helping patients gain meaningful insights and relief in a controlled and supportive environment.

postpartum depression treatment

When should I seek help for postpartum depression?

If symptoms last longer than two weeks, worsen over time, or make it difficult to care for yourself or your baby, it’s important to seek help. Postpartum depression is treatable, and intervention can make a big difference. 

Where can I find treatment and clinical trials for postpartum depression?

Pacific Neuroscience Institute® (PNI) in Santa Monica offers leading-edge psychedelic-assisted therapy treatment and a currently enrolling clinical trial. 

If you or someone you love is struggling with PPD, visit PNI’s Treatment & Research In Psychedelics (TRIP) Center at PacificTRIP.org.

Send us an inquiry or call 310-582-7611 to speak with a compassionate specialist.